所属部门：西北大学食品科学与工程学院

职务/职称：讲师

研究方向：食品微生态健康

电子邮件：zengxj@nwu.edu.cn

个人简介：曾雪君，女，中共党员，工学博士。主要研究内内容包括肿瘤与肠道微环境、益生菌与肠道健康。先后在Food Research International、Food & Function、Journal of Agricultural and Food Chemistry、Food Chemistry、Food Microbiology、Journal of the Science of Food and Agriculture、Toxins、Foods等国际学术期刊发表SCI论文20余篇，主持国家自然科学基金青年项目1项，参与西安市农业重点产业链关键技术攻关项目1项，参与新疆维吾尔自治区自然科学基金面上项目1项。

研究成果：

一、发表文章

1. Xuejun Zeng, Yuwei Wang, Hang Jia, Zhouli Wang, Zhenpeng Gao, Yane Luo, Qinglin Sheng, Yahong Yuan^*, Tianli Yue^*. Metagenomic analysis of microflora structure and functional capacity in probiotic Tibetan kefir grains. Food Research International, 2021, 151, 110849. （IF=8.1）

2. Xuejun Zeng, Hang Jia, Xiao Zhang, Xin Wang, Zhouli Wang, Zhenpeng Gao, Yahong Yuan^*, Tianli Yue^*. Supplementation of kefir ameliorates azoxymethane/dextran sulfate sodium induced colorectal cancer by modulating the gut microbiota. Food & Function, 2021, 12(22), 11641-11655. （IF=6.1）

3. Xuejun Zeng, Hang Jia, Yiheng Shi, Ke Chen, Zhouli Wang, Zhenpeng Gao, Yahong Yuan^*, Tianli Yue^*. Lactobacillus kefiranofaciens JKSP109 and Saccharomyces cerevisiae JKSP39 isolated from Tibetan kefir grain co-alleviated AOM/DSS induced inflammation and colorectal carcinogenesis. Food & Function, 2022, 13(13), 6947-6961. （IF=6.1）

4. Xuejun Zeng, Xuejiao Li, Yuan Yue, Xin Wang, Hong Chen, Yuanyuan Gu, Hang Jia, Yining He, Yahong Yuan^*, Tianli Yue^*. Ameliorative effect of Saccharomyces cerevisiae JKSP39 on Fusobacterium nucleatum and DSS induced colitis mice model. Journal of Agricultural and Food Chemistry. 2022, 70(44),14179-14192. （IF=6.1）

5. Xuejun Zeng, Jiahui Li, Xin Wang, Ling Liu, Shiqi Shen, Zhouli Wang, Yahong Yuan^*, Tianli Yue^*. Regulation of Gut Microbiota and Microbial Metabolome of Kefir Supernatant against Fusobacterium nucleatum and DSS-Coinduced Colitis. Journal of Agricultural and Food Chemistry, 2024, 72(7), 3536-3548. （IF=6.1）

6. Hang Jia, Xuejun Zeng, Rui Cai, Zhouli Wang, YahongYuan, TianliYue^*. One-pot synthesis of magnetic self-assembled carrageenan-ε-polylysine composites: A reusable and effective antibacterial agent against Alicyclobacillus acidoterrestris. Food Chemistry, 2021, 360: 130062. （IF=8.8）

7. Hang Jia, Xuejun Zeng, Rui Cai, Zhouli Wang, YahongYuan, TianliYue^*. Fabrication of Epsilon-Polylysine-Based Magnetic Nanoflowers with Effective Antibacterial Activity against Alicyclobacillus acidoterrestris. Journal of Agricultural and Food Chemistry, 2022, 70, 857–868. （IF=6.1）

8. Wang Xin, Zeng Xuejun, Zhang Xiao, Wei Jianping, Zhang Yuxiang, Long Fangyu, Yue Tianli, Yuan Yahong^*. Aspergillus cristatum attenuates DSS-induced intestinal barrier damage through reducing the oxidative stress, regulating short-chain fatty acid and inhibiting MAPK signaling pathways. Journal of the Science of Food and Agriculture, 2022, 103(4), 1736-1748. (IF=4.1)

9. Hang Jia, Xuejun Zeng, Shiqi Fan, Rui Cai, Zhouli Wang, Yahong Yuan, Tianli Yue^*. Silver nanoparticles anchored magnetic self-assembled carboxymethyl cellulose-ε-polylysine hybrids with synergetic antibacterial activity for wound infection therapy. International Journal of Biological Macromolecules, 2022, 210, 703-715. （IF=8.2）

10. Pascaline Bahati, Xuejun Zeng, Ferdinand Uzizerimana, Ariunsaikhan Tsoggerel, Muhammad Awais, Qi, Guo, Rui Cai, Tianli Yue, Yahong Yuan^*. Adsorption Mechanism of Patulin from Apple Juice by Inactivated Lactic Acid Bacteria Isolated from Kefir Grains. Toxins，13(7), 434. （IF=4.2）

11. Yue Qiu, Xinlu Chen, Zhangxi Chen, Xuejun Zeng, Tianli Yue, Yahong Yuan^*. Effects of Selenium Nanoparticles on Preventing Patulin-Induced Liver, Kidney and Gastrointestinal Damage. Foods, 2022, 11(5), 749. （IF=5.2）

12. Yuanyuan Cui, Mengge Ning, Hong Chen, Xuejun Zeng, Yuan Yue, Yahong Yuan, Yue, Tianli Yue^*. Microbial diversity associated with Tibetan kefir grains and its protective effects against ethanol-induced oxidative stress in HepG2 cells. Food Bioscience, 2022, 50, 102151. （IF=5.2）

13. Qiuxia Fan, Yahong Yuan, Hang Jia, Xuejun Zeng, Zhouli Wang, Zhongqiu Hu, Zhenpeng Gao, Tianli Yue^*. Antimicrobial and anti-biofilm activity of thymoquinone against Shigella flexneri. Applied Microbiology and Biotechnology, 2021, 105, 709-4718. （IF=5.2）

14. Hong Chen, Xiaoyu Wang, Yuan Yue, Xin Wang, Xuejun Zeng, Qi Guo, Xiaohai Yan, Gengan Du, Yahong Yuan, Tianli Yue^*. Enrichment and Distribution of Selenium in Pediococcus acidilactici MRS-7: Impact on Its Biochemical Composition, Microstructure, and Gastrointestinal Survival. Journal of Agricultural and Food Chemistry, 2022, 70(47), 14877-14885. （IF=6.1）

15. Ke Chen, Jinyi Yang, Xinyuan Guo, Weiyu Han, Huijuan Wang, Xuejun Zeng, Zhouli Wang, Yahong Yuan, Tianli Yue^*. Microflora structure and functional capacity in Tibetan kefir grains and selenium-enriched Tibetan kefir grains: A metagenomic analysis. Food Microbiology, 2024, 119, 104454. (IF=5.3)

二、科研项目：

1. 西藏雪莲菌发酵乳介导肠道菌群/短链脂肪酸/NF-κB轴缓解微塑料引起的肠损伤作用机制，国家自然科学基金青年项目，3240160770，2024年8月，主持；

2. 农业重点产业链关键技术攻关项目，2024JH-NYZD-0022，2024年4月，参与。

3. 新疆维吾尔自治区自然科学基金面上项目，2024年9月，参与。