所属部门：西北大学食品科学与工程学院

职务/职称：讲师

研究方向：食品微生态健康

电子邮件：zengxj@nwu.edu.cn

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个人简介：曾雪君，女，中共党员，工学博士。主要研究内容包括肿瘤与肠道微环境、益生菌与肠道健康。先后在Food Research International、Food & Function、Journal of Agricultural and Food Chemistry、Food Chemistry、Food Microbiology、Journal of the Science of Food and Agriculture、Toxins、Foods等国际学术期刊发表SCI论文20余篇，主持国家自然科学基金青年项目1项，参与西安市农业重点产业链关键技术攻关项目1项，参与新疆维吾尔自治区自然科学基金面上项目1项。

研究成果：

一、发表文章

1. Xuejun Zeng, Yuwei Wang, Hang Jia, Zhouli Wang, Zhenpeng Gao, Yane Luo, Qinglin Sheng, Yahong Yuan^*, Tianli Yue^*. Metagenomic analysis of microflora structure and functional capacity in probiotic Tibetan kefir grains. Food Research International, 2021, 151, 110849.

2. Xuejun Zeng, Hang Jia, Xiao Zhang, Xin Wang, Zhouli Wang, Zhenpeng Gao, Yahong Yuan^*, Tianli Yue^*. Supplementation of kefir ameliorates azoxymethane/dextran sulfate sodium induced colorectal cancer by modulating the gut microbiota. Food & Function, 2021, 12(22), 11641-11655.

3. Xuejun Zeng, Hang Jia, Yiheng Shi, Ke Chen, Zhouli Wang, Zhenpeng Gao, Yahong Yuan^*, Tianli Yue^*. Lactobacillus kefiranofaciens JKSP109 and Saccharomyces cerevisiae JKSP39 isolated from Tibetan kefir grain co-alleviated AOM/DSS induced inflammation and colorectal carcinogenesis. Food & Function, 2022, 13(13), 6947-6961.

4. Xuejun Zeng, Xuejiao Li, Yuan Yue, Xin Wang, Hong Chen, Yuanyuan Gu, Hang Jia, Yining He, Yahong Yuan^*, Tianli Yue^*. Ameliorative effect of Saccharomyces cerevisiae JKSP39 on Fusobacterium nucleatum and DSS induced colitis mice model. Journal of Agricultural and Food Chemistry. 2022, 70(44),14179-14192.

5. Xuejun Zeng, Jiahui Li, Xin Wang, Ling Liu, Shiqi Shen, Zhouli Wang, Yahong Yuan^*, Tianli Yue^*. Regulation of Gut Microbiota and Microbial Metabolome of Kefir Supernatant against Fusobacterium nucleatum and DSS-Coinduced Colitis. Journal of Agricultural and Food Chemistry, 2024, 72(7), 3536-3548.

6. Hang Jia, Xuejun Zeng, Rui Cai, Zhouli Wang, YahongYuan, TianliYue^*. One-pot synthesis of magnetic self-assembled carrageenan-ε-polylysine composites: A reusable and effective antibacterial agent against Alicyclobacillus acidoterrestris. Food Chemistry, 2021, 360: 130062.

7. Hang Jia, Xuejun Zeng, Rui Cai, Zhouli Wang, YahongYuan, TianliYue^*. Fabrication of Epsilon-Polylysine-Based Magnetic Nanoflowers with Effective Antibacterial Activity against Alicyclobacillus acidoterrestris. Journal of Agricultural and Food Chemistry, 2022, 70, 857–868.

8. Wang Xin, Zeng Xuejun, Zhang Xiao, Wei Jianping, Zhang Yuxiang, Long Fangyu, Yue Tianli, Yuan Yahong^*. Aspergillus cristatum attenuates DSS-induced intestinal barrier damage through reducing the oxidative stress, regulating short-chain fatty acid and inhibiting MAPK signaling pathways. Journal of the Science of Food and Agriculture, 2022, 103(4), 1736-1748. (IF=4.1)

9. Hang Jia, Xuejun Zeng, Shiqi Fan, Rui Cai, Zhouli Wang, Yahong Yuan, Tianli Yue^*. Silver nanoparticles anchored magnetic self-assembled carboxymethyl cellulose-ε-polylysine hybrids with synergetic antibacterial activity for wound infection therapy. International Journal of Biological Macromolecules, 2022, 210, 703-715.

10. Pascaline Bahati, Xuejun Zeng, Ferdinand Uzizerimana, Ariunsaikhan Tsoggerel, Muhammad Awais, Qi, Guo, Rui Cai, Tianli Yue, Yahong Yuan^*. Adsorption Mechanism of Patulin from Apple Juice by Inactivated Lactic Acid Bacteria Isolated from Kefir Grains. Toxins，13(7), 434.

11. Yue Qiu, Xinlu Chen, Zhangxi Chen, Xuejun Zeng, Tianli Yue, Yahong Yuan^*. Effects of Selenium Nanoparticles on Preventing Patulin-Induced Liver, Kidney and Gastrointestinal Damage. Foods, 2022, 11(5), 749.

12. Yuanyuan Cui, Mengge Ning, Hong Chen, Xuejun Zeng, Yuan Yue, Yahong Yuan, Yue, Tianli Yue^*. Microbial diversity associated with Tibetan kefir grains and its protective effects against ethanol-induced oxidative stress in HepG2 cells. Food Bioscience, 2022, 50, 102151.

13. Qiuxia Fan, Yahong Yuan, Hang Jia, Xuejun Zeng, Zhouli Wang, Zhongqiu Hu, Zhenpeng Gao, Tianli Yue^*. Antimicrobial and anti-biofilm activity of thymoquinone against Shigella flexneri. Applied Microbiology and Biotechnology, 2021, 105, 709-4718.

14. Hong Chen, Xiaoyu Wang, Yuan Yue, Xin Wang, Xuejun Zeng, Qi Guo, Xiaohai Yan, Gengan Du, Yahong Yuan, Tianli Yue^*. Enrichment and Distribution of Selenium in Pediococcus acidilactici MRS-7: Impact on Its Biochemical Composition, Microstructure, and Gastrointestinal Survival. Journal of Agricultural and Food Chemistry, 2022, 70(47), 14877-14885.

15. Ke Chen, Jinyi Yang, Xinyuan Guo, Weiyu Han, Huijuan Wang, Xuejun Zeng, Zhouli Wang, Yahong Yuan, Tianli Yue^*. Microflora structure and functional capacity in Tibetan kefir grains and selenium-enriched Tibetan kefir grains: A metagenomic analysis. Food Microbiology, 2024, 119, 104454.

二、科研项目：

1. 国家自然科学基金青年项目，3240160770，2024年8月，主持；

2. 农业重点产业链关键技术攻关项目，2024JH-NYZD-0022，2024年4月，参与。

3. 新疆维吾尔自治区自然科学基金面上项目，2024年9月，参与。